node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SES86058.1 | SES98083.1 | SAMN05216326_10589 | SAMN05216326_10878 | Prephenate dehydrogenase. | Anthranilate synthase component 2. | 0.669 |
SES86058.1 | SET63502.1 | SAMN05216326_10589 | SAMN05216326_1482 | Prephenate dehydrogenase. | Chorismate mutase. | 0.980 |
SES86058.1 | aroA | SAMN05216326_10589 | SAMN05216326_12617 | Prephenate dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.994 |
SES86058.1 | aroC | SAMN05216326_10589 | SAMN05216326_101101 | Prephenate dehydrogenase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.941 |
SES86058.1 | aroE | SAMN05216326_10589 | SAMN05216326_10689 | Prephenate dehydrogenase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.509 |
SES86058.1 | aroK | SAMN05216326_10589 | SAMN05216326_102110 | Prephenate dehydrogenase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.962 |
SES86058.1 | hisC | SAMN05216326_10589 | SAMN05216326_10571 | Prephenate dehydrogenase. | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.982 |
SES86058.1 | hisC-2 | SAMN05216326_10589 | SAMN05216326_1481 | Prephenate dehydrogenase. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.986 |
SES86058.1 | trpA | SAMN05216326_10589 | SAMN05216326_103120 | Prephenate dehydrogenase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.667 |
SES86058.1 | trpE | SAMN05216326_10589 | SAMN05216326_12020 | Prephenate dehydrogenase. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.669 |
SES98083.1 | SES86058.1 | SAMN05216326_10878 | SAMN05216326_10589 | Anthranilate synthase component 2. | Prephenate dehydrogenase. | 0.669 |
SES98083.1 | SET63502.1 | SAMN05216326_10878 | SAMN05216326_1482 | Anthranilate synthase component 2. | Chorismate mutase. | 0.956 |
SES98083.1 | aroA | SAMN05216326_10878 | SAMN05216326_12617 | Anthranilate synthase component 2. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.786 |
SES98083.1 | aroC | SAMN05216326_10878 | SAMN05216326_101101 | Anthranilate synthase component 2. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.966 |
SES98083.1 | aroE | SAMN05216326_10878 | SAMN05216326_10689 | Anthranilate synthase component 2. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.853 |
SES98083.1 | aroK | SAMN05216326_10878 | SAMN05216326_102110 | Anthranilate synthase component 2. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.878 |
SES98083.1 | trpA | SAMN05216326_10878 | SAMN05216326_103120 | Anthranilate synthase component 2. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.989 |
SES98083.1 | trpE | SAMN05216326_10878 | SAMN05216326_12020 | Anthranilate synthase component 2. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.999 |
SET63502.1 | SES86058.1 | SAMN05216326_1482 | SAMN05216326_10589 | Chorismate mutase. | Prephenate dehydrogenase. | 0.980 |
SET63502.1 | SES98083.1 | SAMN05216326_1482 | SAMN05216326_10878 | Chorismate mutase. | Anthranilate synthase component 2. | 0.956 |