Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMP92151.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (794 aa)    
Predicted Functional Partners:
AMP91353.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.994
AMP93083.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.993
AMP93081.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.992
AMP91308.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.989
AMP94005.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.969
AMP93312.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.969
AMP91863.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.968
AMP93357.1
PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.924
AMP93592.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.877
AMP91769.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.874
Your Current Organism:
Legionella pneumophila pascullei
NCBI taxonomy Id: 91890
Other names: ATCC 33737, CCUG 31226 A, CIP 105570, DSM 7515, L. pneumophila subsp. pascullei, Legionella pneumophila subsp. pascullei, NCTC 12273, strain U8W
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