Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMP92570.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)    
Predicted Functional Partners:
AMP92568.1
Enhanced entry protein EnhB; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.828
AMP92569.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.828
pgk
Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family.
      0.723
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
   0.686
AMP92196.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.679
AMP92567.1
Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.650
AMP92565.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.551
AMP92566.1
Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.551
AMP93415.1
NGG1p interacting factor NIF3; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.451
Your Current Organism:
Legionella pneumophila pascullei
NCBI taxonomy Id: 91890
Other names: ATCC 33737, CCUG 31226 A, CIP 105570, DSM 7515, L. pneumophila subsp. pascullei, Legionella pneumophila subsp. pascullei, NCTC 12273, strain U8W
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