STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP92576.1Carbon storage regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)    
Predicted Functional Partners:
AMP92577.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.860
AMP92040.1
Carbon storage regulator CsrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.842
hfq
RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
  
 0.695
deaD
RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
      
 0.559
csrA
Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
     
 0.527
AMP93478.1
Carbon storage regulator CsrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.527
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
       0.496
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
       0.472
AMP92573.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.469
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
       0.455
Your Current Organism:
Legionella pneumophila pascullei
NCBI taxonomy Id: 91890
Other names: ATCC 33737, CCUG 31226 A, CIP 105570, DSM 7515, L. pneumophila subsp. pascullei, Legionella pneumophila subsp. pascullei, NCTC 12273, strain U8W
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.