STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV08_08174Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1043 aa)    
Predicted Functional Partners:
PV08_11169
Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
    
 0.999
PV08_10188
HUN domain-containing protein.
    
 0.970
PV08_09382
Uncharacterized protein.
    
 
 0.843
PV08_08933
WD_REPEATS_REGION domain-containing protein.
  
 
 
 0.840
PV08_11537
Histone H3; Belongs to the histone H3 family.
    
 
 0.792
PV08_04516
Histone H3-like centromeric protein cnp1.
    
 
 0.792
PV08_08175
PHB domain-containing protein.
 
      0.685
PV08_06178
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.665
PV08_06444
DUF2236 domain-containing protein.
    
 
 0.644
PV08_03875
Uncharacterized protein.
    
 
 0.644
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.