STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV08_01922Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (133 aa)    
Predicted Functional Partners:
PV08_04261
Uncharacterized protein.
    
  0.997
PV08_10214
Histone H2B; Belongs to the histone H2B family.
  
 0.987
PV08_06006
Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.
    
 0.971
PV08_09372
Histone H2A; Belongs to the histone H2A family.
   
 0.969
PV08_10213
Histone H2A; Belongs to the histone H2A family.
  
 0.968
PV08_11536
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
  
0.964
PV08_08933
WD_REPEATS_REGION domain-containing protein.
    
 0.964
PV08_03303
WD_REPEATS_REGION domain-containing protein.
    
 0.948
PV08_00705
Uncharacterized protein.
    
 0.945
PV08_04016
Uncharacterized protein.
    
 0.944
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.