STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV08_01436Uncharacterized protein. (384 aa)    
Predicted Functional Partners:
PV08_01902
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
   
 
 0.917
PV08_00321
Structural maintenance of chromosomes protein.
   
 
 0.866
PV08_08105
Ubiquitin-like domain-containing protein.
    
 0.848
PV08_03421
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.820
PV08_10782
Structural maintenance of chromosomes protein.
   
 
 0.800
PV08_01342
Uncharacterized protein.
   
 
 0.788
PV08_02911
SUMO-conjugating enzyme ubc9; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.764
PV08_00487
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.764
PV08_11260
Uncharacterized protein.
    
 0.756
PV08_10474
SP-RING-type domain-containing protein.
    
 0.756
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.