STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV08_06365Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (422 aa)    
Predicted Functional Partners:
PV08_02189
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
 
 
 0.992
PV08_02872
BPL/LPL catalytic domain-containing protein.
  
 
 0.930
PV08_08193
Lipoyl(Octanoyl) transferase.
  
 
 0.874
PV08_02854
Putative_PNPOx domain-containing protein.
  
 
 0.874
PV08_08170
60S ribosomal protein L16; Belongs to the universal ribosomal protein uL13 family.
      0.811
PV08_03554
Nudix hydrolase domain-containing protein.
    
  0.746
PV08_01473
Nfu_N domain-containing protein.
  
 
 0.628
PV08_11780
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
     
 0.620
PV08_02919
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
      0.603
PV08_05301
CN hydrolase domain-containing protein.
     
 0.583
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
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