node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PV08_00664 | PV08_03302 | A0A0D2C958 | A0A0D2A281 | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.952 |
PV08_00664 | PV08_04516 | A0A0D2C958 | A0A0D2C0W4 | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | Histone H3-like centromeric protein cnp1. | 0.968 |
PV08_00664 | PV08_04681 | A0A0D2C958 | A0A0D1ZXY9 | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. | 0.942 |
PV08_00664 | PV08_06178 | A0A0D2C958 | A0A0D1ZTM6 | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.965 |
PV08_00664 | PV08_06444 | A0A0D2C958 | A0A0D1ZUD2 | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | DUF2236 domain-containing protein. | 0.910 |
PV08_00664 | PV08_07798 | A0A0D2C958 | A0A0D1YJB3 | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | Uncharacterized protein. | 0.924 |
PV08_00664 | PV08_09267 | A0A0D2C958 | A0A0D2AZA8 | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. | 0.918 |
PV08_00664 | PV08_10213 | A0A0D2C958 | A0A0D2BHR1 | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | Histone H2A; Belongs to the histone H2A family. | 0.953 |
PV08_00664 | PV08_10214 | A0A0D2C958 | A0A0D2AWU6 | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | Histone H2B; Belongs to the histone H2B family. | 0.940 |
PV08_00664 | PV08_11537 | A0A0D2C958 | A0A0D2AV46 | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | Histone H3; Belongs to the histone H3 family. | 0.969 |
PV08_03302 | PV08_00664 | A0A0D2A281 | A0A0D2C958 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | 0.952 |
PV08_03302 | PV08_04516 | A0A0D2A281 | A0A0D2C0W4 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Histone H3-like centromeric protein cnp1. | 0.940 |
PV08_03302 | PV08_04681 | A0A0D2A281 | A0A0D1ZXY9 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. | 0.769 |
PV08_03302 | PV08_06178 | A0A0D2A281 | A0A0D1ZTM6 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.955 |
PV08_03302 | PV08_06444 | A0A0D2A281 | A0A0D1ZUD2 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DUF2236 domain-containing protein. | 0.424 |
PV08_03302 | PV08_10213 | A0A0D2A281 | A0A0D2BHR1 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Histone H2A; Belongs to the histone H2A family. | 0.939 |
PV08_03302 | PV08_10214 | A0A0D2A281 | A0A0D2AWU6 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Histone H2B; Belongs to the histone H2B family. | 0.933 |
PV08_03302 | PV08_11537 | A0A0D2A281 | A0A0D2AV46 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Histone H3; Belongs to the histone H3 family. | 0.940 |
PV08_04516 | PV08_00664 | A0A0D2C0W4 | A0A0D2C958 | Histone H3-like centromeric protein cnp1. | Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. | 0.968 |
PV08_04516 | PV08_03302 | A0A0D2C0W4 | A0A0D2A281 | Histone H3-like centromeric protein cnp1. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.940 |