Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pi4k2aPhosphatidylinositol 4-kinase type 2-alpha. (424 aa)    
Predicted Functional Partners:
pi4kb
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
    
 0.934
PI4KA
Phosphatidylinositol 4-kinase alpha; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. PR/SET subfamily.
    
 0.934
Synj1
Synaptojanin-1.
     
 0.893
Pikfyve
1-phosphatidylinositol 3-phosphate 5-kinase.
     
 0.892
Pip5k1a
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha.
     
 0.888
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
     
 0.884
Ocrl
Inositol polyphosphate 5-phosphatase OCRL-1.
     
 0.880
Inpp5e
72 kDa inositol polyphosphate 5-phosphatase.
     
 0.880
HIP1
Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
     
 0.873
PTEN
annotation not available
     
 0.868
Your Current Organism:
Trichinella sp. T6
NCBI taxonomy Id: 92179
Other names: T. sp. T6, Trichinella T6
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