| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HIP1 | Inpp5e | A0A0V0W761 | A0A0V0X673 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 72 kDa inositol polyphosphate 5-phosphatase. | 0.482 |
| HIP1 | Ocrl | A0A0V0W761 | A0A0V0WK25 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Inositol polyphosphate 5-phosphatase OCRL-1. | 0.547 |
| HIP1 | PI4KA | A0A0V0W761 | A0A0V0X5B5 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Phosphatidylinositol 4-kinase alpha; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. PR/SET subfamily. | 0.865 |
| HIP1 | PTEN | A0A0V0W761 | A0A0V0WPE7 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | annotation not available | 0.585 |
| HIP1 | Pikfyve | A0A0V0W761 | A0A0V0WDD2 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 1-phosphatidylinositol 3-phosphate 5-kinase. | 0.876 |
| HIP1 | pi4k2a | A0A0V0W761 | A0A0V0WEX2 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Phosphatidylinositol 4-kinase type 2-alpha. | 0.873 |
| HIP1 | pi4kb | A0A0V0W761 | A0A0V0W560 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. | 0.880 |
| HIP1 | pik3c3 | A0A0V0W761 | A0A0V0X1D6 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Phosphatidylinositol 3-kinase catalytic subunit type 3. | 0.876 |
| Inpp5e | HIP1 | A0A0V0X673 | A0A0V0W761 | 72 kDa inositol polyphosphate 5-phosphatase. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.482 |
| Inpp5e | Ocrl | A0A0V0X673 | A0A0V0WK25 | 72 kDa inositol polyphosphate 5-phosphatase. | Inositol polyphosphate 5-phosphatase OCRL-1. | 0.898 |
| Inpp5e | PI4KA | A0A0V0X673 | A0A0V0X5B5 | 72 kDa inositol polyphosphate 5-phosphatase. | Phosphatidylinositol 4-kinase alpha; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. PR/SET subfamily. | 0.909 |
| Inpp5e | PTEN | A0A0V0X673 | A0A0V0WPE7 | 72 kDa inositol polyphosphate 5-phosphatase. | annotation not available | 0.895 |
| Inpp5e | Pikfyve | A0A0V0X673 | A0A0V0WDD2 | 72 kDa inositol polyphosphate 5-phosphatase. | 1-phosphatidylinositol 3-phosphate 5-kinase. | 0.886 |
| Inpp5e | Pip5k1a | A0A0V0X673 | A0A0V0X648 | 72 kDa inositol polyphosphate 5-phosphatase. | Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha. | 0.895 |
| Inpp5e | Synj1 | A0A0V0X673 | A0A0V0WZD4 | 72 kDa inositol polyphosphate 5-phosphatase. | Synaptojanin-1. | 0.901 |
| Inpp5e | pi4k2a | A0A0V0X673 | A0A0V0WEX2 | 72 kDa inositol polyphosphate 5-phosphatase. | Phosphatidylinositol 4-kinase type 2-alpha. | 0.880 |
| Inpp5e | pi4kb | A0A0V0X673 | A0A0V0W560 | 72 kDa inositol polyphosphate 5-phosphatase. | Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. | 0.903 |
| Ocrl | HIP1 | A0A0V0WK25 | A0A0V0W761 | Inositol polyphosphate 5-phosphatase OCRL-1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.547 |
| Ocrl | Inpp5e | A0A0V0WK25 | A0A0V0X673 | Inositol polyphosphate 5-phosphatase OCRL-1. | 72 kDa inositol polyphosphate 5-phosphatase. | 0.898 |
| Ocrl | PI4KA | A0A0V0WK25 | A0A0V0X5B5 | Inositol polyphosphate 5-phosphatase OCRL-1. | Phosphatidylinositol 4-kinase alpha; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. PR/SET subfamily. | 0.932 |