Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trip12E3 ubiquitin-protein ligase TRIP12. (2098 aa)    
Predicted Functional Partners:
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.998
Ube2n
Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.993
let-70
Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.993
Usp7
Ubiquitin carboxyl-terminal hydrolase 7.
   
 
 0.991
Ube4b
Ubiquitin conjugation factor E4 B.
   
 0.984
RpL40
Ubiquitin-60S ribosomal protein L40.
   
  0.979
UBA1
Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
   
 0.979
UBA52
Ubiquitin-60S ribosomal protein L40.
   
  0.979
Pros45
26S protease regulatory subunit 8.
    
 
 0.977
Ube2k
Ubiquitin-conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.972
Your Current Organism:
Trichinella sp. T6
NCBI taxonomy Id: 92179
Other names: T. sp. T6, Trichinella T6
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