Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TPK1Thiamin pyrophosphokinase 1. (267 aa)    
Predicted Functional Partners:
F38B2.4
Adenylate kinase isoenzyme 1; Belongs to the adenylate kinase family.
     
 0.906
adk
Adenylate kinase isoenzyme 5.
     
 0.878
EPB41L5
Band 4.1-like protein 5.
     
  0.872
SLC25A19
Mitochondrial thiamine pyrophosphate carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.718
SLC34A1-2
Transketolase-like protein 2.
     
 0.710
TOP1
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
     
  0.675
C29F7.3
UMP-CMP kinase 1; Belongs to the adenylate kinase family.
     
 0.667
atp4a
Potassium-transporting ATPase alpha chain 1.
    
 0.620
Atpalpha
Sodium/potassium-transporting ATPase subunit alpha.
    
 0.620
Atpalpha-2
Sodium/potassium-transporting ATPase subunit alpha.
    
 0.620
Your Current Organism:
Trichinella sp. T6
NCBI taxonomy Id: 92179
Other names: T. sp. T6, Trichinella T6
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.