Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HUS1Checkpoint protein; Belongs to the HUS1 family. (294 aa)    
Predicted Functional Partners:
Rad1
Cell cycle checkpoint protein RAD1.
    
 0.999
Rad9a
Cell cycle checkpoint control protein; Belongs to the rad9 family.
    
 0.999
RAD17
Cell cycle checkpoint protein RAD17.
   
 0.995
ATR
Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.
   
 0.992
Rfc4
Replication factor C subunit 4.
   
 0.988
RFC2
Replication factor C subunit 2.
    
 0.982
RFC3
Replication factor C subunit 3.
    
 0.977
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.975
fen1
Flap endonuclease 1.
    
 0.972
Rfc5
Replication factor C subunit 5.
    
 0.966
Your Current Organism:
Trichinella sp. T6
NCBI taxonomy Id: 92179
Other names: T. sp. T6, Trichinella T6
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