Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hmu-2Halomucin; Belongs to the tetraspanin (TM4SF) family. (563 aa)    
Predicted Functional Partners:
KDM6A
Lysine-specific demethylase 6A.
    
 0.930
sem-5
Sex muscle abnormal protein 5.
    
  0.803
SEC22B
Vesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family.
    
 0.792
Ykt6
Synaptobrevin-like protein YKT6; Belongs to the synaptobrevin family.
    
 0.776
tp53
Cellular tumor antigen p53.
    
 0.765
MMAB
Histone-lysine N-methyltransferase SETD1B-A.
    
 0.732
Stx12
Syntaxin-12; Belongs to the syntaxin family.
    
 0.715
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 0.712
T06_14617
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.700
Kmt2e
Histone-lysine N-methyltransferase 2E.
    
 0.700
Your Current Organism:
Trichinella sp. T6
NCBI taxonomy Id: 92179
Other names: T. sp. T6, Trichinella T6
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