Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XRCC1DNA repair protein XRCC1. (516 aa)    
Predicted Functional Partners:
Pnkp
Bifunctional polynucleotide phosphatase/kinase.
   
 0.982
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.981
POLL
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    
 0.978
TDP1
Tyrosyl-DNA phosphodiesterase 1.
   
 
 0.977
ERCC1
DNA excision repair protein ERCC-1.
     
 0.974
Xpac
DNA repair protein complementing XP-A cells-like protein.
     
 0.973
T06_16530
DNA polymerase.
   
 0.971
lig1
DNA ligase.
   
 0.958
PARP1
Poly [ADP-ribose] polymerase.
    
 
 0.957
hay
DNA excision repair protein haywire.
     
 0.953
Your Current Organism:
Trichinella sp. T6
NCBI taxonomy Id: 92179
Other names: T. sp. T6, Trichinella T6
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