Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
bratBrain tumor protein. (1206 aa)    
Predicted Functional Partners:
lrk-1
Leucine-rich repeat serine/threonine-protein kinase 1.
    
 0.901
Tonsl
Tonsoku-like protein.
    
 0.855
csnk2a1
Casein kinase II subunit alpha.
    
 0.825
KDM6A
Lysine-specific demethylase 6A.
    
 0.809
Ube2n
Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.798
Ddx58
Putative ATP-dependent RNA helicase DDX58.
    
 0.794
Ankfy1
Ankyrin repeat and FYVE domain-containing protein 1.
    
 0.767
SIRT1
NAD-dependent protein deacetylase sirtuin-1.
    
  0.716
Supt16h
FACT complex subunit SPT16.
    
 
 0.711
Ssrp1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.711
Your Current Organism:
Trichinella sp. T6
NCBI taxonomy Id: 92179
Other names: T. sp. T6, Trichinella T6
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