Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TOX3TOX high mobility group box family member 3. (490 aa)    
Predicted Functional Partners:
ruvbl2
DNA helicase; Belongs to the RuvB family.
   
 0.879
RUVBL1
DNA helicase; Belongs to the RuvB family.
    
 0.864
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.822
GTF2H3
General transcription factor IIH subunit 3.
    
 0.814
ACTL6A
Actin-like protein 6A; Belongs to the actin family.
   
 0.813
ACTL6A-2
Actin-like protein 6A; Belongs to the actin family.
   
 0.813
TAF13
Transcription initiation factor TFIID subunit 13.
    
  0.813
tbp-1
TATA-box-binding protein.
    
 0.803
Supt16h
FACT complex subunit SPT16.
   
 0.802
TAF5
Transcription initiation factor TFIID subunit 5.
   
 0.795
Your Current Organism:
Trichinella sp. T6
NCBI taxonomy Id: 92179
Other names: T. sp. T6, Trichinella T6
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