STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HELZPutative helicase with zinc finger domain. (1929 aa)    
Predicted Functional Partners:
RC3H2
Roquin-2.
   
 
 0.589
GUCY2F
Guanylate cyclase.
      
 0.579
SMYD3
Histone-lysine N-methyltransferase SMYD3.
    
 0.568
AS28_08855
Protein PAT1 2.
    
 
 0.528
PITPNC1
Cytoplasmic phosphatidylinositol transfer protein 1.
      
 0.493
PHF3
PHD finger protein 3.
   
  
 0.474
PIWIL1
Piwi-like 1; Belongs to the argonaute family.
   
 0.439
CTSL
Cathepsin L1; Belongs to the peptidase C1 family.
   
  
 0.428
KMT2E
Histone-lysine N-methyltransferase 2E.
   
 
 0.422
GTF2E2
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
      
 0.422
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.