STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AS28_0157524-hydroxycholesterol 7-alpha-hydroxylase. (448 aa)    
Predicted Functional Partners:
AS28_02160
Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family.
 
 
0.938
CH25H
Cholesterol 25-hydroxylase-like; Belongs to the sterol desaturase family.
   
 0.798
FAXDC2
Fatty acid hydroxylase domain-containing protein 2; Belongs to the sterol desaturase family.
   
 0.798
FDFT1
Squalene synthase.
  
 
 0.761
AS28_13561
Putative ergosterol biosynthetic protein 28.
   
 
 0.747
HSD17B7
3-keto-steroid reductase.
   
 
 0.745
SIGMAR1
Sigma non-opioid intracellular receptor 1.
   
 
 0.741
SQLE
Squalene monooxygenase.
   
 0.730
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
   
 0.666
SDR42E1
Short-chain dehydrogenase/reductase family 42E member 1; Belongs to the 3-beta-HSD family.
   
 0.666
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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