STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN1Tyrosine-protein phosphatase non-receptor type 1. (417 aa)    
Predicted Functional Partners:
INSR
Tyrosine-protein kinase receptor.
   
 0.978
IRS1
Insulin receptor substrate 1.
    
 0.922
IRS4
Insulin receptor substrate 2-B.
    
 0.922
CTNNB1
Catenin beta-1.
    
 0.918
AS28_06345
Tyrosine-protein phosphatase non-receptor type 11.
 
 
 0.877
AS28_08692
Tyrosine-protein phosphatase non-receptor type 11.
 
 
 0.869
IGF1R
Tyrosine-protein kinase receptor.
   
 0.795
JAK2
Tyrosine-protein kinase.
   
 0.761
SRC
Tyrosine-protein kinase.
   
 0.703
STAT3
Signal transducer and activator of transcription.
   
 0.696
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.