STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDCHistidine decarboxylase. (656 aa)    
Predicted Functional Partners:
CNDP2
Cytosolic non-specific dipeptidase.
   
 
 0.935
AS28_05330
Histamine N-methyltransferase.
     
 0.934
CNDP1
Beta-Ala-His dipeptidase.
   
 
 0.921
HAL
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
     
 0.919
ASMTL
N-acetylserotonin O-methyltransferase-like.
   
  
 0.507
DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.
      
 0.505
KMO
Kynurenine 3-monooxygenase.
   
 
 0.492
HRH1
Histamine H1 receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.491
HRH2
Histamine H2 receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.455
AGXT2
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.440
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.