STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AS28_00788Keratin, type II cytoskeletal 73; Belongs to the intermediate filament family. (448 aa)    
Predicted Functional Partners:
MBP
Myelin basic protein.
   
  
 0.649
NES
Tanabin; Belongs to the intermediate filament family.
    
 
 0.648
PVALB
Parvalbumin, muscle; Belongs to the parvalbumin family.
    
 0.600
DCX
Neuronal migration protein doublecortin.
    
 
 0.567
EEF1A2
Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
     
 0.565
EEF1A1
Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
     
 0.565
S100B
Protein S100-B; Belongs to the S-100 family.
   
 
 0.533
BDNF
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.493
SIN3B
Paired amphipathic helix protein Sin3b.
      
 0.493
ALDH1L2
Mitochondrial 10-formyltetrahydrofolate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
      
 0.493
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.