STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE6CPhosphodiesterase. (838 aa)    
Predicted Functional Partners:
GUK1
Guanylate kinase.
   
 
 0.923
GMPR
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
    
 0.908
APRT
Adenine phosphoribosyltransferase.
     
 0.904
ITPA
Inosine triphosphate pyrophosphatase.
     
  0.900
GMPS
GMP synthase [glutamine-hydrolyzing].
     
  0.900
GNAT1
Guanine nucleotide-binding protein G(T) subunit alpha-1.
   
 0.829
GUCY2C
Guanylate cyclase.
   
 0.800
ADCY5
Adenylate cyclase type 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 0.788
NT5E
5'-nucleotidase; Belongs to the 5'-nucleotidase family.
     
 0.786
GUCY2F
Guanylate cyclase.
   
 0.771
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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