STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WWP1NEDD4-like E3 ubiquitin-protein ligase WWP1. (906 aa)    
Predicted Functional Partners:
ITCH
E3 ubiquitin-protein ligase Itchy.
  
 
0.972
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.935
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.924
MDM2
E3 ubiquitin-protein ligase Mdm2.
    
 0.920
NEDD4L
E3 ubiquitin-protein ligase NEDD4-like.
    
0.918
RNF41
E3 ubiquitin-protein ligase NRDP1.
    
 0.908
SMURF2
E3 ubiquitin-protein ligase SMURF2.
     
0.906
UBB
Polyubiquitin.
    
 0.844
EGFR
Receptor protein-tyrosine kinase.
    
 0.842
SMAD7
Mothers against decapentaplegic 7.
    
 0.829
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.