STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N300_02128Proepiregulin. (118 aa)    
Predicted Functional Partners:
N300_15368
Receptor protein-tyrosine kinase.
    
 0.861
N300_06111
Receptor protein-tyrosine kinase.
    
 0.861
N300_15066
Receptor protein-tyrosine kinase.
    
 0.861
N300_13686
Hepatocyte growth factor receptor.
     
 0.857
N300_09956
Macrophage-stimulating protein receptor.
     
 0.852
N300_13758
Tyrosine-protein kinase receptor.
     
 0.838
N300_09241
Tyrosine-protein kinase receptor.
     
 0.835
N300_01821
Fibroblast growth factor receptor 3.
     
 0.826
N300_02129
Amphiregulin.
   
 
 0.818
N300_05150
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
    
0.783
Your Current Organism:
Calypte anna
NCBI taxonomy Id: 9244
Other names: C. anna
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.