STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N300_09980Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)    
Predicted Functional Partners:
N300_09822
Caspase recruitment domain-containing protein 11.
   
 0.955
N300_03112
Inhibitor of nuclear factor kappa-B kinase subunit beta.
    
0.917
N300_07547
Inhibitor of nuclear factor kappa-B kinase subunit alpha.
    
0.900
N300_07226
Neutrophil cytosol factor 1.
   
 0.885
N300_08694
Cytotoxic T-lymphocyte protein 4.
    
 0.883
N300_06343
Proto-oncogene c-Rel.
   
 0.873
N300_01164
Mitogen-activated protein kinase kinase kinase 7.
    
 
0.872
N300_14129
Tyrosine-protein phosphatase non-receptor type 6.
   
 0.872
N300_05018
Protein kinase C alpha type; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
   
 
0.870
N300_10964
RAF proto-oncogene serine/threonine-protein kinase.
    
0.862
Your Current Organism:
Calypte anna
NCBI taxonomy Id: 9244
Other names: C. anna
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