STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N300_04356Very low-density lipoprotein receptor. (827 aa)    
Predicted Functional Partners:
N300_00614
Disabled 1.
    
 0.936
N300_04046
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
    
 0.927
N300_03029
Low-density lipoprotein receptor-related protein 1B.
 
   
0.927
N300_03028
Low-density lipoprotein receptor-related protein 1B.
 
     
0.900
N300_05858
Low density lipoprotein receptor adapter protein 1.
    
 0.900
N300_03027
Low-density lipoprotein receptor-related protein 1B.
 
      0.885
N300_01552
E3 ubiquitin-protein ligase MYLIP.
    
 0.876
N300_05532
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
    
 0.820
N300_08380
Low density lipoprotein receptor adapter protein 1.
    
  0.810
N300_11934
Hepatic triacylglycerol lipase.
    
 0.801
Your Current Organism:
Calypte anna
NCBI taxonomy Id: 9244
Other names: C. anna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.