STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N300_09750P53 apoptosis effector. (189 aa)    
Predicted Functional Partners:
N300_09749
P53 apoptosis effector.
  
  
 
0.828
N300_10645
Plakophilin-3.
   
 
 0.665
N300_03702
Plakophilin-1.
   
 
 0.660
N300_12915
Desmocollin-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 
 0.611
N300_05785
Plakophilin-2.
   
 
 0.591
N300_06147
Junction plakoglobin.
     
 0.570
N300_13337
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
    
 0.539
N300_12913
Desmoglein-2.
     
 0.532
N300_12914
Desmoglein-1-alpha; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
     
 0.532
N300_02815
Catenin delta-2.
     
 0.506
Your Current Organism:
Calypte anna
NCBI taxonomy Id: 9244
Other names: C. anna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.