node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SKA67725.1 | SKA68767.1 | SAMN02745130_00102 | SAMN02745130_00359 | Alpha-ribazole phosphatase. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.826 |
SKA67725.1 | SKA68784.1 | SAMN02745130_00102 | SAMN02745130_00365 | Alpha-ribazole phosphatase. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.400 |
SKA67725.1 | SKA87254.1 | SAMN02745130_00102 | SAMN02745130_02815 | Alpha-ribazole phosphatase. | precorrin-8X methylmutase. | 0.478 |
SKA67725.1 | cobQ | SAMN02745130_00102 | SAMN02745130_00361 | Alpha-ribazole phosphatase. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.696 |
SKA67725.1 | cobS | SAMN02745130_00102 | SAMN02745130_00364 | Alpha-ribazole phosphatase. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.848 |
SKA67725.1 | cobT | SAMN02745130_00102 | SAMN02745130_00362 | Alpha-ribazole phosphatase. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.851 |
SKA67725.1 | cysG | SAMN02745130_00102 | SAMN02745130_03829 | Alpha-ribazole phosphatase. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.403 |
SKA68767.1 | SKA67725.1 | SAMN02745130_00359 | SAMN02745130_00102 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Alpha-ribazole phosphatase. | 0.826 |
SKA68767.1 | SKA68778.1 | SAMN02745130_00359 | SAMN02745130_00363 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Alpha-ribazole phosphatase. | 0.865 |
SKA68767.1 | SKA68784.1 | SAMN02745130_00359 | SAMN02745130_00365 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.936 |
SKA68767.1 | SKA86067.1 | SAMN02745130_00359 | SAMN02745130_02672 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Alpha-ribazole phosphatase. | 0.859 |
SKA68767.1 | SKA87254.1 | SAMN02745130_00359 | SAMN02745130_02815 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | precorrin-8X methylmutase. | 0.857 |
SKA68767.1 | SKA89189.1 | SAMN02745130_00359 | SAMN02745130_03013 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobyrinic acid a,c-diamide synthase. | 0.972 |
SKA68767.1 | cobQ | SAMN02745130_00359 | SAMN02745130_00361 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.988 |
SKA68767.1 | cobS | SAMN02745130_00359 | SAMN02745130_00364 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.974 |
SKA68767.1 | cobT | SAMN02745130_00359 | SAMN02745130_00362 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.996 |
SKA68767.1 | cysG | SAMN02745130_00359 | SAMN02745130_03829 | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.570 |
SKA68778.1 | SKA68767.1 | SAMN02745130_00363 | SAMN02745130_00359 | Alpha-ribazole phosphatase. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.865 |
SKA68778.1 | SKA68784.1 | SAMN02745130_00363 | SAMN02745130_00365 | Alpha-ribazole phosphatase. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.507 |
SKA68778.1 | SKA87254.1 | SAMN02745130_00363 | SAMN02745130_02815 | Alpha-ribazole phosphatase. | precorrin-8X methylmutase. | 0.476 |