node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SKA68305.1 | SKA72488.1 | SAMN02745130_00246 | SAMN02745130_01093 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit. | Indolepyruvate ferredoxin oxidoreductase. | 0.906 |
SKA68305.1 | SKA78083.1 | SAMN02745130_00246 | SAMN02745130_01828 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit. | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.582 |
SKA68305.1 | SKA80893.1 | SAMN02745130_00246 | SAMN02745130_02133 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit. | Glutamate synthase (ferredoxin). | 0.870 |
SKA68305.1 | SKA83892.1 | SAMN02745130_00246 | SAMN02745130_02444 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit. | Acyl transferase domain-containing protein. | 0.920 |
SKA68305.1 | SKA92327.1 | SAMN02745130_00246 | SAMN02745130_03358 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit. | acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.999 |
SKA68305.1 | SKA96038.1 | SAMN02745130_00246 | SAMN02745130_03836 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.933 |
SKA68305.1 | icmF | SAMN02745130_00246 | SAMN02745130_01577 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.923 |
SKA68305.1 | pckA | SAMN02745130_00246 | SAMN02745130_03737 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.527 |
SKA68305.1 | sucC | SAMN02745130_00246 | SAMN02745130_01724 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.623 |
SKA68305.1 | sucD | SAMN02745130_00246 | SAMN02745130_01725 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.588 |
SKA72488.1 | SKA68305.1 | SAMN02745130_01093 | SAMN02745130_00246 | Indolepyruvate ferredoxin oxidoreductase. | 3-methylcrotonoyl-CoA carboxylase, alpha subunit. | 0.906 |
SKA72488.1 | SKA78083.1 | SAMN02745130_01093 | SAMN02745130_01828 | Indolepyruvate ferredoxin oxidoreductase. | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.597 |
SKA72488.1 | SKA80893.1 | SAMN02745130_01093 | SAMN02745130_02133 | Indolepyruvate ferredoxin oxidoreductase. | Glutamate synthase (ferredoxin). | 0.914 |
SKA72488.1 | SKA83892.1 | SAMN02745130_01093 | SAMN02745130_02444 | Indolepyruvate ferredoxin oxidoreductase. | Acyl transferase domain-containing protein. | 0.726 |
SKA72488.1 | SKA92327.1 | SAMN02745130_01093 | SAMN02745130_03358 | Indolepyruvate ferredoxin oxidoreductase. | acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.878 |
SKA72488.1 | SKA96038.1 | SAMN02745130_01093 | SAMN02745130_03836 | Indolepyruvate ferredoxin oxidoreductase. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.899 |
SKA72488.1 | icmF | SAMN02745130_01093 | SAMN02745130_01577 | Indolepyruvate ferredoxin oxidoreductase. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.929 |
SKA72488.1 | pckA | SAMN02745130_01093 | SAMN02745130_03737 | Indolepyruvate ferredoxin oxidoreductase. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. | 0.726 |
SKA72488.1 | sucC | SAMN02745130_01093 | SAMN02745130_01724 | Indolepyruvate ferredoxin oxidoreductase. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.909 |
SKA72488.1 | sucD | SAMN02745130_01093 | SAMN02745130_01725 | Indolepyruvate ferredoxin oxidoreductase. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.913 |