HOOK3 protein (Ornithorhynchus anatinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HOOK3

Hook microtubule tethering protein 3. (722 aa)

Predicted Functional Partners:

DYNC1LI1

0.891

AKTIP

0.792

F7EF12_ORNAN

0.788

FAM160A1

0.696

BICD2

0.689

MCM4

0.627

F7D6K9_ORNAN

0.607

F7ETA7_ORNAN

0.596

FAM160B1

0.594

DYNC1LI2

0.588

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKTIP	F7EF12_ORNAN	ENSOANP00000021158	ENSOANP00000024773	AKT interacting protein.	Uncharacterized protein.	0.833
AKTIP	FAM160A1	ENSOANP00000021158	ENSOANP00000008401	AKT interacting protein.	Family with sequence similarity 160 member A1.	0.820
AKTIP	FAM160B1	ENSOANP00000021158	ENSOANP00000002483	AKT interacting protein.	Family with sequence similarity 160 member B1.	0.524
AKTIP	HOOK3	ENSOANP00000021158	ENSOANP00000001081	AKT interacting protein.	Hook microtubule tethering protein 3.	0.792
BICD2	DYNC1LI1	ENSOANP00000010835	ENSOANP00000015970	BICD cargo adaptor 2.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.989
BICD2	DYNC1LI2	ENSOANP00000010835	ENSOANP00000025301	BICD cargo adaptor 2.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.654
BICD2	HOOK3	ENSOANP00000010835	ENSOANP00000001081	BICD cargo adaptor 2.	Hook microtubule tethering protein 3.	0.689
DYNC1LI1	BICD2	ENSOANP00000015970	ENSOANP00000010835	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	BICD cargo adaptor 2.	0.989
DYNC1LI1	DYNC1LI2	ENSOANP00000015970	ENSOANP00000025301	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.973
DYNC1LI1	F7D6K9_ORNAN	ENSOANP00000015970	ENSOANP00000017458	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Uncharacterized protein.	0.606
DYNC1LI1	HOOK3	ENSOANP00000015970	ENSOANP00000001081	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Hook microtubule tethering protein 3.	0.891
DYNC1LI2	BICD2	ENSOANP00000025301	ENSOANP00000010835	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	BICD cargo adaptor 2.	0.654
DYNC1LI2	DYNC1LI1	ENSOANP00000025301	ENSOANP00000015970	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.973
DYNC1LI2	F7D6K9_ORNAN	ENSOANP00000025301	ENSOANP00000017458	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Uncharacterized protein.	0.586
DYNC1LI2	HOOK3	ENSOANP00000025301	ENSOANP00000001081	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	Hook microtubule tethering protein 3.	0.588
F7D6K9_ORNAN	DYNC1LI1	ENSOANP00000017458	ENSOANP00000015970	Uncharacterized protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.606
F7D6K9_ORNAN	DYNC1LI2	ENSOANP00000017458	ENSOANP00000025301	Uncharacterized protein.	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.	0.586
F7D6K9_ORNAN	HOOK3	ENSOANP00000017458	ENSOANP00000001081	Uncharacterized protein.	Hook microtubule tethering protein 3.	0.607
F7EF12_ORNAN	AKTIP	ENSOANP00000024773	ENSOANP00000021158	Uncharacterized protein.	AKT interacting protein.	0.833
F7EF12_ORNAN	HOOK3	ENSOANP00000024773	ENSOANP00000001081	Uncharacterized protein.	Hook microtubule tethering protein 3.	0.788