STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MDH2Malate dehydrogenase. (309 aa)    
Predicted Functional Partners:
GOT2
Aspartate aminotransferase.
   
 0.975
FH
Fumarate hydratase.
  
 0.972
F7AGN3_ORNAN
Uncharacterized protein.
  
 0.956
CS
Citrate synthase; Belongs to the citrate synthase family.
  
 0.956
K7EH97_ORNAN
Aminotran_1_2 domain-containing protein.
   
 0.956
F6YGN7_ORNAN
4Fe-4S ferredoxin-type domain-containing protein.
  
 
 0.943
DLD
Dihydrolipoyl dehydrogenase.
  
 0.932
ATP5F1A
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 
 0.923
SUCLG1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.917
UQCRC1
Ubiquinol-cytochrome c reductase core protein 1.
   
 
 0.901
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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