STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F7F1F1_ORNANGuanylate cyclase. (1072 aa)    
Predicted Functional Partners:
NPPA
Natriuretic peptide A.
    
 0.925
NUDT2
Nudix hydrolase 2.
     
 0.906
GCH1
GTP_cyclohydroI domain-containing protein.
     
 0.803
NPPC
C-type natriuretic peptide 39; Venom component with vasorelaxant activity. In vitro stimulates the production of cGMP in rat aortic smooth muscle cells and histamine release from rat peritoneal mast cells. Induces relaxation of isolated rat uterus. Induces local edema following subplantar injection into rat hind paw. Forms voltage-dependent cation channels which are weakly selective for potassium relative to sodium, and whose conductance decreases with increasing dehydration energy of the monovalent cation. The activity of the fast cation channels is calcium dependent and is characteri [...]
    
 0.796
F6X3T4_ORNAN
Uncharacterized protein.
    
 0.772
PDE5A
Phosphodiesterase.
   
 0.764
PDE6G
Phosphodiesterase 6G.
   
 
 0.736
PDE6B
Phosphodiesterase.
   
 0.733
PDE6A
Phosphodiesterase.
   
 0.733
F7EIH6_ORNAN
Phosphodiesterase.
   
 0.728
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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