HDAC2 protein (Ornithorhynchus anatinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD5	F7ENN8_ORNAN	ENSOANP00000002890	ENSOANP00000024745	Chromodomain helicase DNA binding protein 5.	Uncharacterized protein.	0.956
CHD5	H2AZ2	ENSOANP00000002890	ENSOANP00000014916	Chromodomain helicase DNA binding protein 5.	Histone H2A; Belongs to the histone H2A family.	0.421
CHD5	HDAC2	ENSOANP00000002890	ENSOANP00000005760	Chromodomain helicase DNA binding protein 5.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.971
CHD5	K7E6P8_ORNAN	ENSOANP00000002890	ENSOANP00000029205	Chromodomain helicase DNA binding protein 5.	Uncharacterized protein.	0.900
CHD5	K7E713_ORNAN	ENSOANP00000002890	ENSOANP00000029320	Chromodomain helicase DNA binding protein 5.	MTA_R1 domain-containing protein.	0.977
CHD5	MTA3	ENSOANP00000002890	ENSOANP00000006764	Chromodomain helicase DNA binding protein 5.	SANT domain-containing protein.	0.969
CHD5	RBBP4	ENSOANP00000002890	ENSOANP00000001894	Chromodomain helicase DNA binding protein 5.	RB binding protein 4, chromatin remodeling factor.	0.975
CHD5	RBBP7	ENSOANP00000002890	ENSOANP00000006152	Chromodomain helicase DNA binding protein 5.	RB binding protein 7, chromatin remodeling factor.	0.975
CHD5	SAP30	ENSOANP00000002890	ENSOANP00000018210	Chromodomain helicase DNA binding protein 5.	Sin3A associated protein 30.	0.498
CHD5	SAP30L	ENSOANP00000002890	ENSOANP00000008092	Chromodomain helicase DNA binding protein 5.	SAP30 like.	0.461
F7ENN8_ORNAN	CHD5	ENSOANP00000024745	ENSOANP00000002890	Uncharacterized protein.	Chromodomain helicase DNA binding protein 5.	0.956
F7ENN8_ORNAN	H2AZ2	ENSOANP00000024745	ENSOANP00000014916	Uncharacterized protein.	Histone H2A; Belongs to the histone H2A family.	0.680
F7ENN8_ORNAN	HDAC2	ENSOANP00000024745	ENSOANP00000005760	Uncharacterized protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.953
F7ENN8_ORNAN	K7E713_ORNAN	ENSOANP00000024745	ENSOANP00000029320	Uncharacterized protein.	MTA_R1 domain-containing protein.	0.949
F7ENN8_ORNAN	MTA3	ENSOANP00000024745	ENSOANP00000006764	Uncharacterized protein.	SANT domain-containing protein.	0.870
F7ENN8_ORNAN	RBBP4	ENSOANP00000024745	ENSOANP00000001894	Uncharacterized protein.	RB binding protein 4, chromatin remodeling factor.	0.904
F7ENN8_ORNAN	RBBP7	ENSOANP00000024745	ENSOANP00000006152	Uncharacterized protein.	RB binding protein 7, chromatin remodeling factor.	0.904
F7ENN8_ORNAN	SAP30	ENSOANP00000024745	ENSOANP00000018210	Uncharacterized protein.	Sin3A associated protein 30.	0.656
F7ENN8_ORNAN	SAP30L	ENSOANP00000024745	ENSOANP00000008092	Uncharacterized protein.	SAP30 like.	0.549
H2AZ2	CHD5	ENSOANP00000014916	ENSOANP00000002890	Histone H2A; Belongs to the histone H2A family.	Chromodomain helicase DNA binding protein 5.	0.421