STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GIT2GIT ArfGAP 2. (805 aa)    
Predicted Functional Partners:
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.965
CDC42
Cell division cycle 42.
    
 0.953
ADSL
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
      0.863
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.799
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.799
K7EDU4_ORNAN
Uncharacterized protein.
    
 0.799
PAK3
Non-specific serine/threonine protein kinase.
    
 0.751
PAK1
Non-specific serine/threonine protein kinase.
    
 0.751
K7EFV2_ORNAN
GIT1_C domain-containing protein.
    
0.739
FKBP4
Peptidylprolyl isomerase.
 
    
 0.707
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.