STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS15Transmembrane serine protease 15; Belongs to the peptidase S1 family. (1090 aa)    
Predicted Functional Partners:
SLC5A1
Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.711
TXN
Thioredoxin; Belongs to the thioredoxin family.
    
 
 0.706
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
    
 
 0.644
F7CAL5_ORNAN
Uncharacterized protein.
   
 0.615
F6VUK4_ORNAN
Kazal-like domain-containing protein.
    
 0.580
K7EA49_ORNAN
Uncharacterized protein.
   
 0.529
F7DQY6_ORNAN
Uncharacterized protein.
    
 0.527
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
 0.509
ARG2
Uncharacterized protein; Belongs to the arginase family.
   
 0.509
K7EFS9_ORNAN
Thioredoxin; Belongs to the thioredoxin family.
    
 0.491
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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