STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (468 aa)    
Predicted Functional Partners:
NFKB1
RHD domain-containing protein.
   
 0.980
MAP3K14
Protein kinase domain-containing protein.
  
 
0.959
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
0.945
AKT1
Uncharacterized protein.
   
 0.945
MAP2K2
Protein kinase domain-containing protein.
  
0.944
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
0.930
CHUK
Protein kinase domain-containing protein.
    
0.927
K7E7K1_ORNAN
RHD domain-containing protein.
   
 0.808
K7EHF1_ORNAN
ANK_REP_REGION domain-containing protein.
   
 0.808
PDCD10
Programmed cell death 10.
    
 
 0.719
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.