STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (242 aa)    
Predicted Functional Partners:
TNFRSF6B
TNFR-Cys domain-containing protein.
   
 0.963
TNFRSF11B
TNF receptor superfamily member 11b.
   
 0.705
F6ZK10_ORNAN
Uncharacterized protein.
   
 0.685
F6RQJ8_ORNAN
Ig-like domain-containing protein.
      
 0.552
TNFSF11
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
     
 0.539
TNFSF13B
TNF superfamily member 13b; Belongs to the tumor necrosis factor family.
   
 
 0.519
F6RAG0_ORNAN
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
     
 0.498
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.493
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.489
TNFRSF11A
Uncharacterized protein.
     
 0.465
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
Server load: low (24%) [HD]