STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NR4A2Nuclear receptor subfamily 4 group A member 2. (518 aa)    
Predicted Functional Partners:
PITX3
Homeobox protein.
    
 
 0.612
EGR3
Early growth response 3.
   
 
 0.569
NR4A3
Nuclear receptor subfamily 4 group A member 3.
  
  
0.550
RXRA
Retinoid X receptor alpha.
    
0.541
CRYM
Uncharacterized protein.
      
 0.491
SLC18A2
Solute carrier family 18 member A2.
      
 0.485
NCOR2
Nuclear receptor corepressor 2.
    
 0.457
NCOR1
Nuclear receptor corepressor 1.
    
 0.457
NCOR2-2
SANT domain-containing protein.
    
 0.457
F6TRR2_ORNAN
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
     
 0.452
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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