STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (445 aa)    
Predicted Functional Partners:
TBXAS1
Thromboxane A synthase 1; Belongs to the cytochrome P450 family.
   
 
 0.954
PTGS2
Prostaglandin-endoperoxide synthase 2.
   
 0.952
PTGES3
Prostaglandin E synthase 3.
     
 0.952
PTGS1
Prostaglandin-endoperoxide synthase 1.
   
 0.933
HPGDS
Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.
   
 
 0.929
PTGES2
Uncharacterized protein.
     
 0.917
SQLE
Squalene epoxidase.
  
 0.770
ERG28
Ergosterol biosynthesis 28 homolog.
   
 
 0.742
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.734
FAXDC2
Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family.
   
 0.734
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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