MCM2 protein (Ornithorhynchus anatinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MCM2

DNA helicase; Belongs to the MCM family. (908 aa)

Predicted Functional Partners:

ORC3

0.999

MCM4

0.999

MCM6

0.999

ORC4

0.999

MCM5

0.999

CDC7

0.999

ORC5

0.999

MCM3

0.999

F6TS55_ORNAN

0.998

ORC2

0.997

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC7	F6TS55_ORNAN	ENSOANP00000023290	ENSOANP00000015143	Cell division cycle 7; Belongs to the protein kinase superfamily.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.910
CDC7	MCM2	ENSOANP00000023290	ENSOANP00000011401	Cell division cycle 7; Belongs to the protein kinase superfamily.	DNA helicase; Belongs to the MCM family.	0.999
CDC7	MCM3	ENSOANP00000023290	ENSOANP00000030803	Cell division cycle 7; Belongs to the protein kinase superfamily.	MCM_OB domain-containing protein.	0.998
CDC7	MCM4	ENSOANP00000023290	ENSOANP00000011566	Cell division cycle 7; Belongs to the protein kinase superfamily.	DNA helicase; Belongs to the MCM family.	0.999
CDC7	MCM5	ENSOANP00000023290	ENSOANP00000017224	Cell division cycle 7; Belongs to the protein kinase superfamily.	DNA helicase; Belongs to the MCM family.	0.989
CDC7	MCM6	ENSOANP00000023290	ENSOANP00000012709	Cell division cycle 7; Belongs to the protein kinase superfamily.	MCM domain-containing protein; Belongs to the MCM family.	0.995
CDC7	ORC2	ENSOANP00000023290	ENSOANP00000016003	Cell division cycle 7; Belongs to the protein kinase superfamily.	Origin recognition complex subunit 2.	0.787
CDC7	ORC3	ENSOANP00000023290	ENSOANP00000000855	Cell division cycle 7; Belongs to the protein kinase superfamily.	Origin recognition complex subunit 3.	0.826
CDC7	ORC4	ENSOANP00000023290	ENSOANP00000013319	Cell division cycle 7; Belongs to the protein kinase superfamily.	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.	0.850
CDC7	ORC5	ENSOANP00000023290	ENSOANP00000023674	Cell division cycle 7; Belongs to the protein kinase superfamily.	Origin recognition complex subunit 5.	0.914
F6TS55_ORNAN	CDC7	ENSOANP00000015143	ENSOANP00000023290	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Cell division cycle 7; Belongs to the protein kinase superfamily.	0.910
F6TS55_ORNAN	MCM2	ENSOANP00000015143	ENSOANP00000011401	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.998
F6TS55_ORNAN	MCM3	ENSOANP00000015143	ENSOANP00000030803	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	MCM_OB domain-containing protein.	0.996
F6TS55_ORNAN	MCM4	ENSOANP00000015143	ENSOANP00000011566	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.996
F6TS55_ORNAN	MCM5	ENSOANP00000015143	ENSOANP00000017224	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.996
F6TS55_ORNAN	MCM6	ENSOANP00000015143	ENSOANP00000012709	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	MCM domain-containing protein; Belongs to the MCM family.	0.977
F6TS55_ORNAN	ORC2	ENSOANP00000015143	ENSOANP00000016003	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Origin recognition complex subunit 2.	0.989
F6TS55_ORNAN	ORC3	ENSOANP00000015143	ENSOANP00000000855	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Origin recognition complex subunit 3.	0.999
F6TS55_ORNAN	ORC4	ENSOANP00000015143	ENSOANP00000013319	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.	0.999
F6TS55_ORNAN	ORC5	ENSOANP00000015143	ENSOANP00000023674	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Origin recognition complex subunit 5.	0.999