RD3 protein (Ornithorhynchus anatinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RD3

Retinal degeneration 3, GUCY2D regulator. (197 aa)

Predicted Functional Partners:

SUCO

0.624

PRPH2

0.605

F6U3S1_ORNAN

0.583

FGF5

0.581

F7FYX1_ORNAN

0.559

AIPL1

0.549

NEK2

0.515

IMPDH1

0.502

IQCB1

0.499

SPATA7

0.476

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIPL1	F6U3S1_ORNAN	ENSOANP00000028429	ENSOANP00000020197	Aryl hydrocarbon receptor interacting protein like 1.	Uncharacterized protein.	0.591
AIPL1	F7FYX1_ORNAN	ENSOANP00000028429	ENSOANP00000007986	Aryl hydrocarbon receptor interacting protein like 1.	Lebercilin domain-containing protein.	0.530
AIPL1	IMPDH1	ENSOANP00000028429	ENSOANP00000001261	Aryl hydrocarbon receptor interacting protein like 1.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.501
AIPL1	PRPH2	ENSOANP00000028429	ENSOANP00000013457	Aryl hydrocarbon receptor interacting protein like 1.	Peripherin 2.	0.487
AIPL1	RD3	ENSOANP00000028429	ENSOANP00000013486	Aryl hydrocarbon receptor interacting protein like 1.	Retinal degeneration 3, GUCY2D regulator.	0.549
F6U3S1_ORNAN	AIPL1	ENSOANP00000020197	ENSOANP00000028429	Uncharacterized protein.	Aryl hydrocarbon receptor interacting protein like 1.	0.591
F6U3S1_ORNAN	F7FYX1_ORNAN	ENSOANP00000020197	ENSOANP00000007986	Uncharacterized protein.	Lebercilin domain-containing protein.	0.554
F6U3S1_ORNAN	IMPDH1	ENSOANP00000020197	ENSOANP00000001261	Uncharacterized protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.544
F6U3S1_ORNAN	IQCB1	ENSOANP00000020197	ENSOANP00000027360	Uncharacterized protein.	Uncharacterized protein.	0.499
F6U3S1_ORNAN	RD3	ENSOANP00000020197	ENSOANP00000013486	Uncharacterized protein.	Retinal degeneration 3, GUCY2D regulator.	0.583
F7FYX1_ORNAN	AIPL1	ENSOANP00000007986	ENSOANP00000028429	Lebercilin domain-containing protein.	Aryl hydrocarbon receptor interacting protein like 1.	0.530
F7FYX1_ORNAN	F6U3S1_ORNAN	ENSOANP00000007986	ENSOANP00000020197	Lebercilin domain-containing protein.	Uncharacterized protein.	0.554
F7FYX1_ORNAN	IMPDH1	ENSOANP00000007986	ENSOANP00000001261	Lebercilin domain-containing protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	0.433
F7FYX1_ORNAN	IQCB1	ENSOANP00000007986	ENSOANP00000027360	Lebercilin domain-containing protein.	Uncharacterized protein.	0.426
F7FYX1_ORNAN	RD3	ENSOANP00000007986	ENSOANP00000013486	Lebercilin domain-containing protein.	Retinal degeneration 3, GUCY2D regulator.	0.559
F7FYX1_ORNAN	SPATA7	ENSOANP00000007986	ENSOANP00000028467	Lebercilin domain-containing protein.	Uncharacterized protein.	0.402
FGF5	RD3	ENSOANP00000005659	ENSOANP00000013486	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Retinal degeneration 3, GUCY2D regulator.	0.581
IMPDH1	AIPL1	ENSOANP00000001261	ENSOANP00000028429	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	Aryl hydrocarbon receptor interacting protein like 1.	0.501
IMPDH1	F6U3S1_ORNAN	ENSOANP00000001261	ENSOANP00000020197	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	Uncharacterized protein.	0.544
IMPDH1	F7FYX1_ORNAN	ENSOANP00000001261	ENSOANP00000007986	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.	Lebercilin domain-containing protein.	0.433