STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NDRG1N-myc downstream regulated 1. (388 aa)    
Predicted Functional Partners:
MYCN
MYCN proto-oncogene, bHLH transcription factor.
    
 
 0.610
SGK3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.571
VASH1
Vasohibin 1.
      
 0.568
LCP2
Lymphocyte cytosolic protein 2.
    
 
 0.500
NDRG2
NDRG family member 2.
  
 
  
0.493
ARHGEF10
Rho guanine nucleotide exchange factor 10.
   
  
 0.489
RAB3GAP1
RAB3 GTPase activating protein catalytic subunit 1.
      
 0.478
TP63
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
    
 0.429
TP53
P53 domain-containing protein.
    
 0.423
SGK1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.410
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.