STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (477 aa)    
Predicted Functional Partners:
PDPK1
Protein kinase domain-containing protein.
  
0.983
MDM2
MDM2 proto-oncogene.
    
 0.973
FOXO3
Fork-head domain-containing protein.
    
 0.970
FOXO1
Forkhead box O1.
    
 0.970
HSP90AA1
Heat shock protein 90 alpha family class A member 1.
    
 0.962
PIK3R2
Uncharacterized protein.
   
 0.961
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
0.961
TSC1
Uncharacterized protein.
    
 0.961
CHUK
Protein kinase domain-containing protein.
   
0.960
PHLPP1
Uncharacterized protein.
 
  
 0.960
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.