node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F6U6U0_ORNAN | IL1B | ENSOANP00000016716 | ENSOANP00000016712 | Interleukin-1. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.430 |
F6U6U0_ORNAN | IL1F10 | ENSOANP00000016716 | ENSOANP00000016719 | Interleukin-1. | Interleukin-1. | 0.441 |
F6U6U0_ORNAN | IL1R1 | ENSOANP00000016716 | ENSOANP00000017691 | Interleukin-1. | Interleukin 1 receptor type 1. | 0.643 |
F6U6U0_ORNAN | IL1RAP | ENSOANP00000016716 | ENSOANP00000007050 | Interleukin-1. | Interleukin 1 receptor accessory protein. | 0.586 |
F6U6U0_ORNAN | MYD88 | ENSOANP00000016716 | ENSOANP00000001873 | Interleukin-1. | MYD88 innate immune signal transduction adaptor. | 0.425 |
IL1B | F6U6U0_ORNAN | ENSOANP00000016712 | ENSOANP00000016716 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1. | 0.430 |
IL1B | IL1R1 | ENSOANP00000016712 | ENSOANP00000017691 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin 1 receptor type 1. | 0.992 |
IL1B | IL1R2 | ENSOANP00000016712 | ENSOANP00000013081 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Uncharacterized protein. | 0.997 |
IL1B | IL1RAP | ENSOANP00000016712 | ENSOANP00000007050 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin 1 receptor accessory protein. | 0.981 |
IL1B | IL1RN | ENSOANP00000016712 | ENSOANP00000016720 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin-1. | 0.410 |
IL1B | IRAK1 | ENSOANP00000016712 | ENSOANP00000017468 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Interleukin 1 receptor associated kinase 1. | 0.747 |
IL1B | IRAK4 | ENSOANP00000016712 | ENSOANP00000003026 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | Protein kinase domain-containing protein. | 0.642 |
IL1B | MYD88 | ENSOANP00000016712 | ENSOANP00000001873 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | MYD88 innate immune signal transduction adaptor. | 0.848 |
IL1B | TRAF6 | ENSOANP00000016712 | ENSOANP00000018657 | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.777 |
IL1F10 | F6U6U0_ORNAN | ENSOANP00000016719 | ENSOANP00000016716 | Interleukin-1. | Interleukin-1. | 0.441 |
IL1F10 | IL1R1 | ENSOANP00000016719 | ENSOANP00000017691 | Interleukin-1. | Interleukin 1 receptor type 1. | 0.709 |
IL1F10 | IL1RAP | ENSOANP00000016719 | ENSOANP00000007050 | Interleukin-1. | Interleukin 1 receptor accessory protein. | 0.467 |
IL1F10 | MYD88 | ENSOANP00000016719 | ENSOANP00000001873 | Interleukin-1. | MYD88 innate immune signal transduction adaptor. | 0.436 |
IL1R1 | F6U6U0_ORNAN | ENSOANP00000017691 | ENSOANP00000016716 | Interleukin 1 receptor type 1. | Interleukin-1. | 0.643 |
IL1R1 | IL1B | ENSOANP00000017691 | ENSOANP00000016712 | Interleukin 1 receptor type 1. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.992 |