STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECTD2HECT domain E3 ubiquitin protein ligase 2. (661 aa)    
Predicted Functional Partners:
F6R9G8_ORNAN
Uncharacterized protein.
 
      0.642
UBE2L6
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.568
TRIP12
Thyroid hormone receptor interactor 12.
   
 
0.560
K7EE40_ORNAN
Uncharacterized protein.
   
 
 0.560
UBE2L3
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.506
UBE2N
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.440
ARIH1
RBR-type E3 ubiquitin transferase.
   
 
 0.432
PCGF5
Polycomb group ring finger 5.
 
  
 
 0.423
UBA3
Ubiquitin like modifier activating enzyme 3.
   
 0.411
SEC31A
WD_REPEATS_REGION domain-containing protein.
 
      0.404
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.