STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOK2Docking protein 2. (431 aa)    
Predicted Functional Partners:
LCK
Tyrosine-protein kinase.
   
 0.751
RASA1
RAS p21 protein activator 1.
   
 
 0.731
TEK
TEK receptor tyrosine kinase.
    
 0.714
F6ZPJ2_ORNAN
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.617
F6PMZ1_ORNAN
Uncharacterized protein.
    
 0.617
TIE1
EGF-like domain-containing protein.
    
 0.617
F7C1Q5_ORNAN
Uncharacterized protein.
     
 0.593
CRK
CRK proto-oncogene, adaptor protein.
    
 0.589
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.588
GFRA2
GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
     
 0.577
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.