STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAD3SMAD family member 3. (293 aa)    
Predicted Functional Partners:
K7EEQ4_ORNAN
MH1 domain-containing protein.
 
 0.988
SKI
Uncharacterized protein.
   
 0.885
SMAD4
Mothers against decapentaplegic homolog.
   
0.862
F6QMQ5_ORNAN
MSC domain-containing protein.
   
 
 0.803
ZFYVE16
Zinc finger FYVE domain-containing protein.
   
 0.789
SKIL
c-SKI_SMAD_bind domain-containing protein.
   
 0.766
F7CS48_ORNAN
Uncharacterized protein.
   
 0.766
CTNNB1
Catenin beta 1.
  
 0.750
K7ECP7_ORNAN
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
  
 0.727
NEDD4
E3 ubiquitin-protein ligase.
    
 0.707
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.