F6PNP5_ORNAN protein (Ornithorhynchus anatinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

F6PNP5_ORNAN

Uncharacterized protein. (159 aa)

Predicted Functional Partners:

F7B8C6_ORNAN

0.961

MRI1

0.833

MTHFR

0.744

APIP

0.722

F6RQS2_ORNAN

0.722

KYAT1

0.621

GPT

0.621

KYAT3

0.621

F7GCB7_ORNAN

0.621

HYKK

0.621

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APIP	F6PNP5_ORNAN	ENSOANP00000011768	ENSOANP00000023942	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	Uncharacterized protein.	0.722
APIP	F7B8C6_ORNAN	ENSOANP00000011768	ENSOANP00000024399	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	Uncharacterized protein.	0.830
APIP	MRI1	ENSOANP00000011768	ENSOANP00000019619	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.985
F6PNP5_ORNAN	APIP	ENSOANP00000023942	ENSOANP00000011768	Uncharacterized protein.	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	0.722
F6PNP5_ORNAN	F6RQS2_ORNAN	ENSOANP00000023942	ENSOANP00000017162	Uncharacterized protein.	Aldolase_II domain-containing protein.	0.722
F6PNP5_ORNAN	F7B8C6_ORNAN	ENSOANP00000023942	ENSOANP00000024399	Uncharacterized protein.	Uncharacterized protein.	0.961
F6PNP5_ORNAN	F7GCB7_ORNAN	ENSOANP00000023942	ENSOANP00000014657	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.621
F6PNP5_ORNAN	GPT	ENSOANP00000023942	ENSOANP00000005582	Uncharacterized protein.	Glutamic--pyruvic transaminase.	0.621
F6PNP5_ORNAN	HYKK	ENSOANP00000023942	ENSOANP00000020882	Uncharacterized protein.	Hydroxylysine kinase.	0.621
F6PNP5_ORNAN	KYAT1	ENSOANP00000023942	ENSOANP00000005294	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.621
F6PNP5_ORNAN	KYAT3	ENSOANP00000023942	ENSOANP00000014530	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.621
F6PNP5_ORNAN	MRI1	ENSOANP00000023942	ENSOANP00000019619	Uncharacterized protein.	Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.833
F6PNP5_ORNAN	MTHFR	ENSOANP00000023942	ENSOANP00000004365	Uncharacterized protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.744
F6RQS2_ORNAN	F6PNP5_ORNAN	ENSOANP00000017162	ENSOANP00000023942	Aldolase_II domain-containing protein.	Uncharacterized protein.	0.722
F6RQS2_ORNAN	F7B8C6_ORNAN	ENSOANP00000017162	ENSOANP00000024399	Aldolase_II domain-containing protein.	Uncharacterized protein.	0.791
F6RQS2_ORNAN	MRI1	ENSOANP00000017162	ENSOANP00000019619	Aldolase_II domain-containing protein.	Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.832
F7B8C6_ORNAN	APIP	ENSOANP00000024399	ENSOANP00000011768	Uncharacterized protein.	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.	0.830
F7B8C6_ORNAN	F6PNP5_ORNAN	ENSOANP00000024399	ENSOANP00000023942	Uncharacterized protein.	Uncharacterized protein.	0.961
F7B8C6_ORNAN	F6RQS2_ORNAN	ENSOANP00000024399	ENSOANP00000017162	Uncharacterized protein.	Aldolase_II domain-containing protein.	0.791
F7B8C6_ORNAN	MRI1	ENSOANP00000024399	ENSOANP00000019619	Uncharacterized protein.	Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family.	0.968