DYSF protein (Ornithorhynchus anatinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DYSF

Peroxin/Ferlin domain-containing protein. (87 aa)

Predicted Functional Partners:

DSC1

0.502

FAT3

0.499

FBN3

0.497

FBN3-2

0.497

ANXA2

0.452

DUPD1

0.452

RPL5

0.448

ANXA1

0.436

TRIM72

0.408

FAT2

0.407

Your Current Organism:

Ornithorhynchus anatinus

NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA1	ANXA2	ENSOANP00000020763	ENSOANP00000019528	Annexin.	Annexin.	0.946
ANXA1	DYSF	ENSOANP00000020763	ENSOANP00000030437	Annexin.	Peroxin/Ferlin domain-containing protein.	0.436
ANXA1	TRIM72	ENSOANP00000020763	ENSOANP00000002202	Annexin.	Tripartite motif containing 72.	0.630
ANXA2	ANXA1	ENSOANP00000019528	ENSOANP00000020763	Annexin.	Annexin.	0.946
ANXA2	DYSF	ENSOANP00000019528	ENSOANP00000030437	Annexin.	Peroxin/Ferlin domain-containing protein.	0.452
ANXA2	TRIM72	ENSOANP00000019528	ENSOANP00000002202	Annexin.	Tripartite motif containing 72.	0.555
DSC1	DYSF	ENSOANP00000008954	ENSOANP00000030437	Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Peroxin/Ferlin domain-containing protein.	0.502
DSC1	FBN3	ENSOANP00000008954	ENSOANP00000010191	Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Fibrillin 3.	0.530
DSC1	FBN3-2	ENSOANP00000008954	ENSOANP00000032162	Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	EGF-like domain-containing protein.	0.530
DUPD1	DYSF	ENSOANP00000032004	ENSOANP00000030437	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Peroxin/Ferlin domain-containing protein.	0.452
DUPD1	RPL5	ENSOANP00000032004	ENSOANP00000007399	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Ribosomal_L18_c domain-containing protein.	0.607
DYSF	ANXA1	ENSOANP00000030437	ENSOANP00000020763	Peroxin/Ferlin domain-containing protein.	Annexin.	0.436
DYSF	ANXA2	ENSOANP00000030437	ENSOANP00000019528	Peroxin/Ferlin domain-containing protein.	Annexin.	0.452
DYSF	DSC1	ENSOANP00000030437	ENSOANP00000008954	Peroxin/Ferlin domain-containing protein.	Desmocollin 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.502
DYSF	DUPD1	ENSOANP00000030437	ENSOANP00000032004	Peroxin/Ferlin domain-containing protein.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.452
DYSF	FAT2	ENSOANP00000030437	ENSOANP00000008120	Peroxin/Ferlin domain-containing protein.	FAT atypical cadherin 2.	0.407
DYSF	FAT3	ENSOANP00000030437	ENSOANP00000018549	Peroxin/Ferlin domain-containing protein.	FAT atypical cadherin 3.	0.499
DYSF	FBN3	ENSOANP00000030437	ENSOANP00000010191	Peroxin/Ferlin domain-containing protein.	Fibrillin 3.	0.497
DYSF	FBN3-2	ENSOANP00000030437	ENSOANP00000032162	Peroxin/Ferlin domain-containing protein.	EGF-like domain-containing protein.	0.497
DYSF	RPL5	ENSOANP00000030437	ENSOANP00000007399	Peroxin/Ferlin domain-containing protein.	Ribosomal_L18_c domain-containing protein.	0.448